6eld | pdb_00006eld
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Crystal structure of TIA-1 RRM1 in complex with U1C
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Structural highlights
Function[TIA1_HUMAN] Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis. Contents | ||||||||||||||||
This page was last modified 09:12, 11 November 2020.