6j0z | pdb_00006j0z

Crystal structure of AlpK

spinqualitylabelsall models 6j0z, resolution 2.89Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6j0z is a 1 chain structure with sequence from Streptomyces ambofaciens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.889Å Ligands: FAD Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function Q6VMI4_STRAM Publication Abstract from PubMed AlpK is an essential monooxygenase involved in the biosynthesis of kinamycin. It catalyzes the C5-hyfroxylattion of the crucial benzo[b]-fluorence intermediate in kinamycin synthesis. However, the structure and mechanism of AlpK is unclear. Here, we report the first structure of AlpK in complex with FAD. Our structure sheds light on the catalytic mechanism of AlpK. Crystal structure of AlpK: An essential monooxygenase involved in the biosynthesis of kinamycin.,Wang W, Li J, Li H, Fan K, Liu Y Biochem Biophys Res Commun. 2019 Mar 19;510(4):601-605. doi:, 10.1016/j.bbrc.2019.01.077. Epub 2019 Feb 7. PMID:30739782 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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