7pmx

HsPepT1 bound to Ala-Phe in the outward facing open conformation

spinqualitylabelsall models 7pmx, resolution 3.50Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7pmx is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.5Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function S15A1_HUMAN Proton-coupled amino-acid transporter that transports oligopeptides of 2 to 4 amino acids with a preference for dipeptides (PubMed:7896779, PubMed:18367661, PubMed:19685173). Primarily responsible for the absorption of dietary di- and tripeptides from the small intestinal lumen (By similarity).[UniProtKB:P36836] Publication Abstract from PubMed [Figure: see text]. Structural snapshots of human PepT1 and PepT2 reveal mechanistic insights into substrate and drug transport across epithelial membranes.,Killer M, Wald J, Pieprzyk J, Marlovits TC, Low C Sci Adv. 2021 Nov 5;7(45):eabk3259. doi: 10.1126/sciadv.abk3259. Epub 2021 Nov 3. PMID:34730990 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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