8exf | pdb_00008exf

Crystal structure of human FAM46A-BCCIPa complex at 3.2 angstrom resolution

spinqualitylabelsall models 8exf, resolution 3.22Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8exf is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 3.22Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease TET5A_HUMAN Osteogenesis imperfecta type 3. The disease is caused by variants affecting the gene represented in this entry. Function TET5A_HUMAN Cytoplasmic non-canonical poly(A) RNA polymerase that catalyzes the transfer of one adenosine molecule from an ATP to an mRNA poly(A) tail bearing a 3'-OH terminal group and participates in the cytoplasmic polyadenylation (PubMed:33882302). Polyadenylates mRNA encoding extracellular matrix constituents and other genes crucial for bone mineralization and during osteoblast mineralization, mainly focuses on ER-targeted mRNAs (By similarity).[UniProtKB:D3Z5S8]

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