8gs3 | pdb_00008gs3

Cryo-EM structure of human Neuroligin 3

spinqualitylabelsall models 8gs3, resolution 3.90Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8gs3 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.9Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease NLGN3_HUMAN NON RARE IN EUROPE: Autism;NON RARE IN EUROPE: Asperger syndrome. Disease susceptibility is associated with variants affecting the gene represented in this entry. Function NLGN3_HUMAN Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and may mediate its effects by clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system (By similarity).

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