MTOR signaling pathway
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mTOR (mammalian target of Rapamycin) integrates the input from insulin, growth factors and amino acids. Rapamycin inhibits mTOR by association with FKBP12[1]. mTOR functions as a serine/threonine protein kinase that regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis, autophagy, and transcription.
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This page was last modified 10:55, 5 April 2022.