Transferrin

spinqualitylabelsall models Glycosylated human transferrin with Fe+3 (light red), carbonate and sulfate (PDB code 3qyt). Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Transferrin or serotransferrin (TF) is an iron-binding protein. TF delivers iron from absorption centers in the duodendum and white blood cell macrophages to all tissues. Ovotransferrin (OTF) is a glycosylated TF of egg white. For details see Molecular Playground/Transferrin. Relevance Carbohydrate-deficient TF may help diagnose alcoholic liver disease. Structural highlights TF contains two lobes: at the N and C termini. The Fe+3 ion is coordinated to several side chains belonging to both N- and C-lobe, carbonate and sulfate ions. N-lobe Fe coordination site. C-lobe Fe coordination site. 3D Structures of Transferrin Transferrin 3D structures

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