3i28 | pdb_00003i28

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File:3i28.jpg

Template:STRUCTURE 3i28

Crystal Structure of soluble epoxide Hydrolase

Template:ABSTRACT PUBMED 19746975

Disease

Known disease associated with this structure: Hypercholesterolemia, familial, due to LDLR defect, modifier of OMIM:[132811]

About this Structure

3I28 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Eldrup AB, Soleymanzadeh F, Taylor SJ, Muegge I, Farrow NA, Joseph D, McKellop K, Man CC, Kukulka A, De Lombaert S. Structure-based optimization of arylamides as inhibitors of soluble epoxide hydrolase. J Med Chem. 2009 Oct 8;52(19):5880-95. PMID:19746975 doi:10.1021/jm9005302

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