3i68 | pdb_00003i68

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File:3i68.png

Template:STRUCTURE 3i68

Plasmodium falciparum dihydroorotate dehydrogenase bound with triazolopyrimidine-based inhibitor DSM2

Template:ABSTRACT PUBMED 19640844

About this Structure

3I68 is a 1 chain structure of sequence from Plasmodium falciparum 3d7. Full crystallographic information is available from OCA.

Reference

  1. Deng X, Gujjar R, El Mazouni F, Kaminsky W, Malmquist NA, Goldsmith EJ, Rathod PK, Phillips MA. Structural plasticity of malaria dihydroorotate dehydrogenase allows selective binding of diverse chemical scaffolds. J Biol Chem. 2009 Sep 25;284(39):26999-7009. Epub 2009 Jul 28. PMID:19640844 doi:10.1074/jbc.M109.028589

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