3jz1 | pdb_00003jz1
From Proteopedia
Crystal structure of human thrombin mutant N143P in E:Na+ form
Disease
Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]
About this Structure
3JZ1 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Pineda AO, Carrell CJ, Bush LA, Prasad S, Caccia S, Chen ZW, Mathews FS, Di Cera E. Molecular dissection of Na+ binding to thrombin. J Biol Chem. 2004 Jul 23;279(30):31842-53. Epub 2004 May 19. PMID:15152000 doi:https://dx.doi.org/10.1074/jbc.M401756200
- Gandhi PS, Chen Z, Mathews FS, Di Cera E. Structural identification of the pathway of long-range communication in an allosteric enzyme. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):1832-7. Epub 2008 Feb 4. PMID:18250335
Page seeded by OCA on Wed Oct 21 10:42:05 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Thrombin
- Bah, A.
- Bush-Pelc, L A.
- Cera, E Di.
- Chen, Z.
- Gandhi, P S.
- Niu, W.
- Acute phase
- Blood coagulation
- Calcium
- Cleavage on pair of basic residue
- Disease mutation
- Disulfide bond
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydrolase
- Kringle
- Pharmaceutical
- Polymorphism
- Protease
- Secreted
- Serine protease
- Zymogen
