3hle | pdb_00003hle

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Template:ABSTRACT PUBMED 19875080

File:3hle.png


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3hle, resolution 2.06Å (default scene)
Ligands: DTT, MJA
Related: 1hld
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



Simvastatin Synthase (LovD), from Aspergillus terreus, S5 mutant, S76A mutant, complex with monacolin J acid

About this Structure

3HLE is a 1 chain structure of sequence from Aspergillus terreus. Full crystallographic information is available from OCA.

Reference

  1. Gao X, Xie X, Pashkov I, Sawaya MR, Laidman J, Zhang W, Cacho R, Yeates TO, Tang Y. Directed evolution and structural characterization of a simvastatin synthase. Chem Biol. 2009 Oct 30;16(10):1064-74. PMID:19875080 doi:10.1016/j.chembiol.2009.09.017

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