3e4z | pdb_00003e4z

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Template:STRUCTURE 3e4z

File:3e4z.png

Crystal structure of human insulin degrading enzyme in complex with insulin-like growth factor II

Template:ABSTRACT PUBMED 19896952

Disease

Known disease associated with this structure: Intrauterine and postnatal growth retardation OMIM:[147470]

About this Structure

3E4Z is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Guo Q, Manolopoulou M, Bian Y, Schilling AB, Tang WJ. Molecular basis for the recognition and cleavages of IGF-II, TGF-alpha, and amylin by human insulin-degrading enzyme. J Mol Biol. 2010 Jan 15;395(2):430-43. Epub 2009 Nov 5. PMID:19896952 doi:10.1016/j.jmb.2009.10.072

Page seeded by OCA on Wed Dec 9 14:02:12 2009

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