3jqa | pdb_00003jqa

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File:3jqa.jpg

Template:STRUCTURE 3jqa

Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor (NADP+) and inhibitor 2-amino-1,9-dihydro-6H-purine-6-thione (DX4)

Template:ABSTRACT PUBMED 19916554

About this Structure

3JQA is a 4 chains structure of sequences from Trypanosoma brucei. Full crystallographic information is available from OCA.

Reference

  1. Tulloch LB, Martini VP, Iulek J, Huggan JK, Lee JH, Gibson CL, Smith TK, Suckling CJ, Hunter WN. Structure-Based Design of Pteridine Reductase Inhibitors Targeting African Sleeping Sickness and the Leishmaniases. J Med Chem. 2009 Nov 16. PMID:19916554 doi:10.1021/jm901059x

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