3k9x | pdb_00003k9x
From Proteopedia
X-ray crystal structure of human fxa in complex with (S)-N-((2-METHYLBENZOFURAN-5-YLAMINO)(2-OXO-1-(2-OXO-2- (PYRROLIDIN-1-YL)ETHYL)AZEPAN-3- YLAMINO)METHYLENE)NICOTINAMIDE
Template:ABSTRACT PUBMED 19896847
About this Structure
3K9X is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Shi Y, Li C, O'Connor SP, Zhang J, Shi M, Bisaha SN, Wang Y, Sitkoff D, Pudzianowski AT, Huang C, Klei HE, Kish K, Yanchunas J Jr, Liu EC, Hartl KS, Seiler SM, Steinbacher TE, Schumacher WA, Atwal KS, Stein PD. Aroylguanidine-based factor Xa inhibitors: the discovery of BMS-344577. Bioorg Med Chem Lett. 2009 Dec 15;19(24):6882-9. Epub 2009 Oct 23. PMID:19896847 doi:10.1016/j.bmcl.2009.10.084
Page seeded by OCA on Wed Dec 16 13:09:13 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Coagulation factor Xa
- Homo sapiens
- Ghosh, K.
- Kish, K.
- Klei, H E.
- Rushith, A.
- Blood clotting
- Blood coagulation
- Blood coagulation factor
- Calcium
- Cleavage on pair of basic residue
- Disulfide bond
- Egf-like domain
- Epidermal growth factor like domain
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydrolase
- Hydroxylation
- Polymorphism
- Protease
- Secreted
- Serine protease
- Zymogen