2wkz | pdb_00002wkz

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Template:STRUCTURE 2wkz

File:2wkz.jpg

HIV-1 PROTEASE INHIBITORS CONTAINING A TERTIARY ALCOHOL IN THE TRANSITION-STATE MIMIC WITH IMPROVED CELL-BASED ANTIVIRAL ACTIVITY

Template:ABSTRACT PUBMED 19961222

About this Structure

2WKZ is a 2 chains structure of sequences from Human immunodeficiency virus type 1 (isolate z2/cdc-z34 group m subtype d). Full crystallographic information is available from OCA.

Reference

  1. Mahalingam AK, Axelsson L, Ekegren JK, Wannberg J, Kihlstrom J, Unge T, Wallberg H, Samuelsson B, Larhed M, Hallberg A. HIV-1 Protease Inhibitors with a Transition-State Mimic Comprising a Tertiary Alcohol: Improved Antiviral Activity in Cells. J Med Chem. 2009 Dec 4. PMID:19961222 doi:10.1021/jm901165g

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