3ewu | pdb_00003ewu
From Proteopedia
D312N mutant of human orotidyl-5'-monophosphate decarboxylase in complex with 6-acetyl-UMP, covalent adduct
Template:ABSTRACT PUBMED 19472232
Disease
Known disease associated with this structure: Oroticaciduria OMIM:[258900]
About this Structure
3EWU is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Heinrich D, Diederichsen U, Rudolph MG. Lys314 is a nucleophile in non-classical reactions of orotidine-5'-monophosphate decarboxylase. Chemistry. 2009 Jul 6;15(27):6619-25. PMID:19472232 doi:10.1002/chem.200900397
Page seeded by OCA on Wed Dec 16 13:34:00 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Orotidine-5'-phosphate decarboxylase
- Diederichsen, U.
- Heinrich, D.
- Rudolph, M.
- Wittmann, J.
- Alternative splicing
- Decarboxylase
- Decarboxylation
- Disease mutation
- Glycosyltransferase
- Lyase
- Multifunctional enzyme
- Polymorphism
- Pyrimidine biosynthesis
- Tim barrel
- Transferase
- Unusual catalysis
