3kcf | pdb_00003kcf
From Proteopedia
Crystal structure of TGFbRI complexed with a pyrazolone inhibitor
About this Structure
3KCF is a 5 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Guckian K, Carter MB, Lin EY, Choi M, Sun L, Boriack-Sjodin PA, Chuaqui C, Lane B, Cheung K, Ling L, Lee WC. Pyrazolone based TGFbetaR1 kinase inhibitors. Bioorg Med Chem Lett. 2010 Jan 1;20(1):326-9. Epub 2009 Oct 29. PMID:19914068 doi:10.1016/j.bmcl.2009.10.108
Page seeded by OCA on Wed Dec 23 09:45:36 2009
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Categories:
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- Homo sapiens
- Receptor protein serine/threonine kinase
- Boriack-Sjodin, P A.
- Aortic aneurysm
- Atp-binding
- Craniosynostosis
- Disease mutation
- Disulfide bond
- Glycoprotein
- Kinase
- Magnesium
- Manganese
- Membrane
- Metal-binding
- Nucleotide-binding
- Phosphoprotein
- Polymorphism
- Protein-inhibitor complex
- Receptor
- Serine/threonine-protein kinase
- Structure-based drug design
- Tgfbetari
- Transferase
- Transmembrane