1w6k | pdb_00001w6k

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Template:STRUCTURE 1w6k

File:1w6k.png

STRUCTURE OF HUMAN OSC IN COMPLEX WITH LANOSTEROL

Template:ABSTRACT PUBMED 15525992

About this Structure

1W6K is a 1 chain structure with sequence from Homo sapiens. The December 2007 RCSB PDB Molecule of the Month feature on Oxidosqualene Cyclase by David S. Goodsell is 10.2210/rcsb_pdb/mom_2007_12. Full crystallographic information is available from OCA.

Reference

Thoma R, Schulz-Gasch T, D'Arcy B, Benz J, Aebi J, Dehmlow H, Hennig M, Stihle M, Ruf A. Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase. Nature. 2004 Nov 4;432(7013):118-22. PMID:15525992 doi:10.1038/nature02993
Ruf A, Muller F, D'Arcy B, Stihle M, Kusznir E, Handschin C, Morand OH, Thoma R. The monotopic membrane protein human oxidosqualene cyclase is active as monomer. Biochem Biophys Res Commun. 2004 Mar 5;315(2):247-54. PMID:14766201 doi:10.1016/j.bbrc.2004.01.052

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[1] Thoma R, Schulz-Gasch T, D'Arcy B, Benz J, Aebi J, Dehmlow H, Hennig M, Stihle M, Ruf A. Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase. Nature. 2004 Nov 4;432(7013):118-22. PMID:15525992 doi:10.1038/nature02993

[2] Ruf A, Muller F, D'Arcy B, Stihle M, Kusznir E, Handschin C, Morand OH, Thoma R. The monotopic membrane protein human oxidosqualene cyclase is active as monomer. Biochem Biophys Res Commun. 2004 Mar 5;315(2):247-54. PMID:14766201 doi:10.1016/j.bbrc.2004.01.052

1w6k | pdb_00001w6k

STRUCTURE OF HUMAN OSC IN COMPLEX WITH LANOSTEROL

About this Structure

Reference

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