2wxe | pdb_00002wxe
From Proteopedia
THE CRYSTAL STRUCTURE OF THE MURINE CLASS IA PI 3-KINASE P110DELTA IN COMPLEX WITH IC87114.
About this Structure
2WXE is a 1 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.
Reference
- Berndt A, Miller S, Williams O, Le DD, Houseman BT, Pacold JI, Gorrec F, Hon WC, Liu Y, Rommel C, Gaillard P, Ruckle T, Schwarz MK, Shokat KM, Shaw JP, Williams RL. The p110 delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors. Nat Chem Biol. 2010 Feb;6(2):117-24. PMID:20081827 doi:10.1038/nchembio.293
Page seeded by OCA on Wed Jan 27 19:48:05 2010
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Categories:
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- Mus musculus
- Phosphatidylinositol-4,5-bisphosphate 3-kinase
- Berndt, A.
- Gaillard, P.
- Gorrec, F.
- Hon, W C.
- Houseman, B T.
- Lee, D D.
- Liu, Y.
- Miller, S.
- Pacold, J I.
- Rommel, C.
- Ruckle, T.
- Schwarz, M K.
- Shaw, J P.
- Shokat, K M.
- Williams, O.
- Williams, R L.
- Atp-binding
- Cancer
- Isoform-specific inhibitor
- Nucleotide-binding
- Phosphoprotein
- Transferase