3iu3 | pdb_00003iu3

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File:3iu3.jpg

Template:STRUCTURE 3iu3

Crystal structure of the Fab fragment of therapeutic antibody Basiliximab in complex with IL-2Ra (CD25) ectodomain

Template:ABSTRACT PUBMED 20032294

About this Structure

3IU3 is a 9 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Du J, Yang H, Zhang D, Wang J, Guo H, Peng B, Guo Y, Ding J. Structural basis for the blockage of IL-2 signaling by therapeutic antibody basiliximab. J Immunol. 2010 Feb 1;184(3):1361-8. Epub 2009 Dec 23. PMID:20032294 doi:10.4049/jimmunol.0903178

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