3i8w | pdb_00003i8w
From Proteopedia
Crystal structure of a metallacarborane inhibitor bound to HIV protease
About this Structure
3I8W is a 1 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
Reference
- Rezacova P, Pokorna J, Brynda J, Kozisek M, Cigler P, Lepsik M, Fanfrlik J, Rezac J, Grantz Saskova K, Sieglova I, Plesek J, Sicha V, Gruner B, Oberwinkler H, Sedlacek' J, Krausslich HG, Hobza P, Kral V, Konvalinka J. Design of HIV protease inhibitors based on inorganic polyhedral metallacarboranes. J Med Chem. 2009 Nov 26;52(22):7132-41. PMID:19874035 doi:10.1021/jm9011388
Page seeded by OCA on Thu Jan 28 15:13:20 2010
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Categories:
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- HIV-1 retropepsin
- Human immunodeficiency virus 1
- Rezacova, P.
- Aid
- Aspartic protease
- Aspartyl protease
- Capsid maturation
- Capsid protein
- Cell membrane
- Cytoplasm
- Dna integration
- Dna recombination
- Dna-directed dna polymerase
- Endonuclease
- Hydrolase
- Hydrolase/hydrolase inhibitor complex
- Inhibitor
- Lipoprotein
- Magnesium
- Membrane
- Metal-binding
- Multifunctional enzyme
- Myristate
- Nuclease
- Nucleotidyltransferase
- Nucleus
- Phosphoprotein
- Protease
- Ribosomal frameshifting
- Rna-binding
- Rna-directed dna polymerase
- Transferase
- Viral nucleoprotein
- Viral resistance
- Virion
- Zinc
- Zinc-finger