2x38 | pdb_00002x38
From Proteopedia
THE CRYSTAL STRUCTURE OF THE MURINE CLASS IA PI 3-KINASE P110DELTA IN COMPLEX WITH IC87114.
Template:ABSTRACT PUBMED 20081827
About this Structure
2X38 is a 1 chain structure with sequence from Mus musculus. This structure supersedes the now removed PDB entry 2wxe. Full crystallographic information is available from OCA.
Reference
- Berndt A, Miller S, Williams O, Le DD, Houseman BT, Pacold JI, Gorrec F, Hon WC, Liu Y, Rommel C, Gaillard P, Ruckle T, Schwarz MK, Shokat KM, Shaw JP, Williams RL. The p110 delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors. Nat Chem Biol. 2010 Feb;6(2):117-24. PMID:20081827 doi:10.1038/nchembio.293
Page seeded by OCA on Wed Feb 3 09:29:15 2010
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Categories:
- Pages with broken file links
- Mus musculus
- Phosphatidylinositol-4,5-bisphosphate 3-kinase
- Berndt, A.
- Gaillard, P.
- Gorrec, F.
- Hon, W C.
- Houseman, B T.
- Lee, D D.
- Liu, Y.
- Miller, S.
- Pacold, J I.
- Rommel, C.
- Ruckle, T.
- Schwarz, M K.
- Shaw, J P.
- Shokat, K M.
- Williams, O.
- Williams, R L.
- Cancer
- Isoform-specific inhibitor
- Phosphoinositide 3-kinase
- Transferase