2wk3 | pdb_00002wk3

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Template:STRUCTURE 2wk3

File:2wk3.png

CRYSTAL STRUCTURE OF HUMAN INSULIN-DEGRADING ENZYME IN COMPLEX WITH AMYLOID-BETA (1-42)

Template:ABSTRACT PUBMED 19896952

About this Structure

2WK3 is a 4 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Guo Q, Manolopoulou M, Bian Y, Schilling AB, Tang WJ. Molecular basis for the recognition and cleavages of IGF-II, TGF-alpha, and amylin by human insulin-degrading enzyme. J Mol Biol. 2010 Jan 15;395(2):430-43. Epub 2009 Nov 5. PMID:19896952 doi:10.1016/j.jmb.2009.10.072

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