3e50 | pdb_00003e50

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File:3e50.png

Template:STRUCTURE 3e50

Crystal structure of human insulin degrading enzyme in complex with transforming growth factor-alpha

Template:ABSTRACT PUBMED 19896952

About this Structure

3E50 is a 4 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Guo Q, Manolopoulou M, Bian Y, Schilling AB, Tang WJ. Molecular basis for the recognition and cleavages of IGF-II, TGF-alpha, and amylin by human insulin-degrading enzyme. J Mol Biol. 2010 Jan 15;395(2):430-43. Epub 2009 Nov 5. PMID:19896952 doi:10.1016/j.jmb.2009.10.072

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