3iop | pdb_00003iop

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Template:STRUCTURE 3iop

File:3iop.jpg

PDK-1 in complex with the inhibitor Compound-8i

Template:ABSTRACT PUBMED 20074837

About this Structure

3IOP is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Nittoli T, Dushin RG, Ingalls C, Cheung K, Floyd MB, Fraser H, Olland A, Hu Y, Grosu G, Han X, Arndt K, Guo B, Wissner A. The identification of 8,9-dimethoxy-5-(2-aminoalkoxy-pyridin-3-yl)-benzo[c][2,7]naphthyridin-4-y lamines as potent inhibitors of 3-phosphoinositide-dependent kinase-1 (PDK-1). Eur J Med Chem. 2010 Apr;45(4):1379-86. Epub 2009 Dec 28. PMID:20074837 doi:10.1016/j.ejmech.2009.12.036

Page seeded by OCA on Wed Feb 17 10:33:17 2010

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OCA

[1] Nittoli T, Dushin RG, Ingalls C, Cheung K, Floyd MB, Fraser H, Olland A, Hu Y, Grosu G, Han X, Arndt K, Guo B, Wissner A. The identification of 8,9-dimethoxy-5-(2-aminoalkoxy-pyridin-3-yl)-benzo[c][2,7]naphthyridin-4-y lamines as potent inhibitors of 3-phosphoinositide-dependent kinase-1 (PDK-1). Eur J Med Chem. 2010 Apr;45(4):1379-86. Epub 2009 Dec 28. PMID:20074837 doi:10.1016/j.ejmech.2009.12.036

3iop | pdb_00003iop

PDK-1 in complex with the inhibitor Compound-8i

About this Structure

Reference

Proteopedia Page Contributors and Editors (what is this?)

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