3lak | pdb_00003lak

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Template:STRUCTURE 3lak

File:3lak.jpg

Crystal structure of HIV-1 reverse transcriptase in complex with N1-heterocycle pyrimidinedione non-nucleoside inhibitor

Template:ABSTRACT PUBMED 20137928

About this Structure

3LAK is a 2 chains structure with sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  1. Mitchell ML, Son JC, Lee IY, Lee CK, Kim HS, Guo H, Wang J, Hayes J, Wang M, Paul A, Lansdon EB, Chen JM, Eisenberg G, Geleziunas R, Xu L, Kim CU. N1-Heterocyclic pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1585-8. Epub 2010 Jan 21. PMID:20137928 doi:10.1016/j.bmcl.2010.01.086

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