3fcs | pdb_00003fcs
From Proteopedia
Structure of complete ectodomain of integrin aIIBb3
Disease
Known disease associated with this structure: Glanzmann thrombasthenia, type A OMIM:[607759], Thrombocytopenia, neonatal alloimmune OMIM:[607759]
About this Structure
3FCS is a 4 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Zhu J, Luo BH, Xiao T, Zhang C, Nishida N, Springer TA. Structure of a complete integrin ectodomain in a physiologic resting state and activation and deactivation by applied forces. Mol Cell. 2008 Dec 26;32(6):849-61. PMID:19111664 doi:10.1016/j.molcel.2008.11.018
Page seeded by OCA on Wed Mar 3 14:57:30 2010
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Luo, B H.
- Nishida, N.
- Springer, T A.
- Xiao, T.
- Zhang, C.
- Zhu, J.
- Alternative splicing
- Beta propeller
- Cell adhesion
- Cell adhesion-blood clotting complex
- Cell adhesion-immune system complex
- Disease mutation
- Egf domain
- Glycoprotein
- Host-virus interaction
- Integrin
- Membrane
- Phosphoprotein
- Polymorphism
- Receptor
- Rossmann fold
- Transmembrane
