3ixj | pdb_00003ixj

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File:3ixj.jpg

Template:STRUCTURE 3ixj

Crystal structure of beta-secretase 1 in complex with selective beta-secretase 1 inhibitor

Template:ABSTRACT PUBMED 20128595

About this Structure

3IXJ is a 3 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Bjorklund C, Oscarson S, Benkestock K, Borkakoti N, Jansson K, Lindberg J, Vrang L, Hallberg A, Rosenquist A, Samuelsson B. Design and synthesis of potent and selective BACE-1 inhibitors. J Med Chem. 2010 Feb 25;53(4):1458-64. PMID:20128595 doi:10.1021/jm901168f

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