2b5t | pdb_00002b5t

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File:2b5t.png

Template:STRUCTURE 2b5t

2.1 Angstrom structure of a nonproductive complex between antithrombin, synthetic heparin mimetic SR123781 and two S195A thrombin molecules

Template:ABSTRACT PUBMED 16973611

Disease

Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]

About this Structure

2B5T is a 5 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Johnson DJ, Langdown J, Li W, Luis SA, Baglin TP, Huntington JA. Crystal structure of monomeric native antithrombin reveals a novel reactive center loop conformation. J Biol Chem. 2006 Nov 17;281(46):35478-86. Epub 2006 Sep 13. PMID:16973611 doi:10.1074/jbc.M607204200

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