3m1n | pdb_00003m1n

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Template:STRUCTURE 3m1n

File:3m1n.jpg

Crystal structure of Human Sonic Hedgehog N-terminal domain

Template:ABSTRACT PUBMED 10753901

Disease

Known disease associated with this structure: Coloboma, ocular OMIM:[600725], Holoprosencephaly-3 OMIM:[600725], Microphthalmia, isolated, with coloboma 5 OMIM:[600725], Solitary median maxillary central incisor OMIM:[600725]

About this Structure

3M1N is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Pepinsky RB, Rayhorn P, Day ES, Dergay A, Williams KP, Galdes A, Taylor FR, Boriack-Sjodin PA, Garber EA. Mapping sonic hedgehog-receptor interactions by steric interference. J Biol Chem. 2000 Apr 14;275(15):10995-1001. PMID:10753901

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