3lu9 | pdb_00003lu9
From Proteopedia
Crystal structure of human thrombin mutant S195A in complex with the extracellular fragment of human PAR1
Disease
Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]
About this Structure
3LU9 is a 6 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Pineda AO, Carrell CJ, Bush LA, Prasad S, Caccia S, Chen ZW, Mathews FS, Di Cera E. Molecular dissection of Na+ binding to thrombin. J Biol Chem. 2004 Jul 23;279(30):31842-53. Epub 2004 May 19. PMID:15152000 doi:https://dx.doi.org/10.1074/jbc.M401756200
Page seeded by OCA on Wed Mar 17 09:47:11 2010
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Categories:
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- Homo sapiens
- Thrombin
- Cera, E Di.
- Chen, Z.
- Gandhi, P S.
- Acute phase
- Blood coagulation
- Calcium
- Cell membrane
- Cleavage on pair of basic residue
- Disease mutation
- Disulfide bond
- G-protein coupled receptor
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydrolase
- Kringle
- Membrane
- Pharmaceutical
- Phosphoprotein
- Polymorphism
- Protease
- Receptor
- Secreted
- Serine protease
- Transducer
- Transmembrane
- Zymogen