2fle | pdb_00002fle

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File:2fle.png

Template:STRUCTURE 2fle

Structural analysis of asymmetric inhibitor bound to the HIV-1 Protease V82A mutant

Template:ABSTRACT PUBMED 18215016

About this Structure

2FLE is a 2 chains structure with sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  1. Clemente JC, Robbins A, Grana P, Paleo MR, Correa JF, Villaverde MC, Sardina FJ, Govindasamy L, Agbandje-McKenna M, McKenna R, Dunn BM, Sussman F. Design, synthesis, evaluation, and crystallographic-based structural studies of HIV-1 protease inhibitors with reduced response to the V82A mutation. J Med Chem. 2008 Feb 28;51(4):852-60. Epub 2008 Jan 24. PMID:18215016 doi:10.1021/jm701170f

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