3ion | pdb_00003ion

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File:3ion.png

Template:STRUCTURE 3ion

PDK1 in complex with Compound 8h

Template:ABSTRACT PUBMED 20074837

About this Structure

3ION is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Nittoli T, Dushin RG, Ingalls C, Cheung K, Floyd MB, Fraser H, Olland A, Hu Y, Grosu G, Han X, Arndt K, Guo B, Wissner A. The identification of 8,9-dimethoxy-5-(2-aminoalkoxy-pyridin-3-yl)-benzo[c][2,7]naphthyridin-4-y lamines as potent inhibitors of 3-phosphoinositide-dependent kinase-1 (PDK-1). Eur J Med Chem. 2010 Apr;45(4):1379-86. Epub 2009 Dec 28. PMID:20074837 doi:10.1016/j.ejmech.2009.12.036

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