3ioi | pdb_00003ioi
From Proteopedia
Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with a novel UDP-Gal derived inhibitor (1GW)
Disease
Known disease associated with this structure: Blood group, ABO system OMIM:[110300]
About this Structure
3IOI is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Pesnot T, Jorgensen R, Palcic MM, Wagner GK. Structural and mechanistic basis for a new mode of glycosyltransferase inhibition. Nat Chem Biol. 2010 May;6(5):321-3. Epub 2010 Apr 4. PMID:20364127 doi:10.1038/nchembio.343
Page seeded by OCA on Wed Apr 28 10:46:38 2010
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Jorgensen, R.
- Palcic, M M.
- Pesnot, T.
- Wagner, G K.
- Abo
- Blood group antigen
- Cisab mutant
- Glycoprotein
- Glycosyltransferase
- Golgi apparatus
- Gta
- Inhibitor
- Manganese
- Membrane
- Metal-binding
- Polymorphism
- Rossman fold
- Secreted
- Semi-closed conformation
- Signal-anchor
- Transferase
- Transmembrane
