3hob | pdb_00003hob

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File:3hob.png

Template:STRUCTURE 3hob

Factor VIII Trp2313-His2315 segment is involved in membrane binding as shown by crystal structure of complex between factor VIII C2 domain and an inhibitor

Template:ABSTRACT PUBMED 20089867

About this Structure

3HOB is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Liu Z, Lin L, Yuan C, Nicolaes GA, Chen L, Meehan EJ, Furie B, Furie B, Huang M. Trp2313-His2315 of factor VIII C2 domain is involved in membrane binding: structure of a complex between the C2 domain and an inhibitor of membrane binding. J Biol Chem. 2010 Mar 19;285(12):8824-9. Epub 2010 Jan 20. PMID:20089867 doi:10.1074/jbc.M109.080168

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