2kqp | pdb_00002kqp

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Template:STRUCTURE 2kqp

File:2kqp.png

NMR Structure of Proinsulin

Template:ABSTRACT PUBMED 20106974

Disease

Known disease associated with this structure: Hyperproinsulinemia, familial, with or without diabetes OMIM:[176730]

About this Structure

2KQP is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  1. Yang Y, Hua QX, Liu J, Shimizu EH, Choquette MH, Mackin RB, Weiss MA. Solution structure of proinsulin: connecting domain flexibility and prohormone processing. J Biol Chem. 2010 Mar 12;285(11):7847-51. Epub 2010 Jan 27. PMID:20106974 doi:10.1074/jbc.C109.084921

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