2kes | pdb_00002kes

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Template:STRUCTURE 2kes

File:2kes.png

Solution Structure of the Coiled-coil Domain of Synphilin-1

Template:ABSTRACT PUBMED 19762560

Disease

Known disease associated with this structure: Parkinson disease OMIM:[603779]

About this Structure

2KES is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  1. Xie YY, Zhou CJ, Zhou ZR, Hong J, Che MX, Fu QS, Song AX, Lin DH, Hu HY. Interaction with synphilin-1 promotes inclusion formation of alpha-synuclein: mechanistic insights and pathological implication. FASEB J. 2010 Jan;24(1):196-205. Epub 2009 Sep 17. PMID:19762560 doi:10.1096/fj.09-133082

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