3l15 | pdb_00003l15

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Template:STRUCTURE 3l15

File:3l15.png

Human Tead2 transcriptional factor

Template:ABSTRACT PUBMED 20368466

About this Structure

3L15 is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Tian W, Yu J, Tomchick DR, Pan D, Luo X. Structural and functional analysis of the YAP-binding domain of human TEAD2. Proc Natl Acad Sci U S A. 2010 Apr 20;107(16):7293-8. Epub 2010 Apr 5. PMID:20368466
  2. Wu S, Liu Y, Zheng Y, Dong J, Pan D. The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway. Dev Cell. 2008 Mar;14(3):388-98. Epub 2008 Feb 7. PMID:18258486 doi:10.1016/j.devcel.2008.01.007
  3. Chan SW, Lim CJ, Loo LS, Chong YF, Huang C, Hong W. TEADs mediate nuclear retention of TAZ to promote oncogenic transformation. J Biol Chem. 2009 May 22;284(21):14347-58. Epub 2009 Mar 26. PMID:19324876 doi:10.1074/jbc.M901568200
  4. Zhao B, Ye X, Yu J, Li L, Li W, Li S, Yu J, Lin JD, Wang CY, Chinnaiyan AM, Lai ZC, Guan KL. TEAD mediates YAP-dependent gene induction and growth control. Genes Dev. 2008 Jul 15;22(14):1962-71. Epub 2008 Jun 25. PMID:18579750 doi:10.1101/gad.1664408

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