3kl6 | pdb_00003kl6

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Template:STRUCTURE 3kl6

File:3kl6.png

Discovery of Tetrahydropyrimidin-2(1H)-one derivative TAK-442: A potent, selective and orally active factor Xa inhibitor

Template:ABSTRACT PUBMED 20355714

Disease

Known disease associated with this structure: Factor X deficiency OMIM:[227600]

About this Structure

3KL6 is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Fujimoto T, Imaeda Y, Konishi N, Hiroe K, Kawamura M, Textor GP, Aertgeerts K, Kubo K. Discovery of a tetrahydropyrimidin-2(1H)-one derivative (TAK-442) as a potent, selective, and orally active factor Xa inhibitor. J Med Chem. 2010 May 13;53(9):3517-31. PMID:20355714 doi:10.1021/jm901699j

Page seeded by OCA on Thu May 20 09:06:26 2010

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OCA

[1] Fujimoto T, Imaeda Y, Konishi N, Hiroe K, Kawamura M, Textor GP, Aertgeerts K, Kubo K. Discovery of a tetrahydropyrimidin-2(1H)-one derivative (TAK-442) as a potent, selective, and orally active factor Xa inhibitor. J Med Chem. 2010 May 13;53(9):3517-31. PMID:20355714 doi:10.1021/jm901699j

3kl6 | pdb_00003kl6

Contents

Discovery of Tetrahydropyrimidin-2(1H)-one derivative TAK-442: A potent, selective and orally active factor Xa inhibitor

Disease

About this Structure

Reference

Proteopedia Page Contributors and Editors (what is this?)

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