3mpm | pdb_00003mpm

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File:3mpm.jpg

Template:STRUCTURE 3mpm

LCK complexed with a pyrazolopyrimidine

Template:ABSTRACT PUBMED 20483608

Disease

Known disease associated with this structure: SCID due to LCK deficiency OMIM:[153390]

About this Structure

3MPM is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Gommermann N, Buehlmayer P, von Matt A, Breitenstein W, Masuya K, Pirard B, Furet P, Cowan-Jacob SW, Weckbecker G. New pyrazolo[1,5a]pyrimidines as orally active inhibitors of Lck. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3628-31. Epub 2010 Apr 29. PMID:20483608 doi:10.1016/j.bmcl.2010.04.112

Page seeded by OCA on Wed Jun 2 08:33:28 2010

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OCA

[1] Gommermann N, Buehlmayer P, von Matt A, Breitenstein W, Masuya K, Pirard B, Furet P, Cowan-Jacob SW, Weckbecker G. New pyrazolo[1,5a]pyrimidines as orally active inhibitors of Lck. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3628-31. Epub 2010 Apr 29. PMID:20483608 doi:10.1016/j.bmcl.2010.04.112

3mpm | pdb_00003mpm

Contents

LCK complexed with a pyrazolopyrimidine

Disease

About this Structure

Reference

Proteopedia Page Contributors and Editors (what is this?)

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