3i25 | pdb_00003i25

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File:3i25.jpg

Template:STRUCTURE 3i25

Potent Beta-Secretase 1 hydroxyethylene Inhibitor

Template:ABSTRACT PUBMED 20122837

About this Structure

3I25 is a 3 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Bjorklund C, Adolfsson H, Jansson K, Lindberg J, Vrang L, Hallberg A, Rosenquist S, Samuelsson B. Discovery of potent BACE-1 inhibitors containing a new hydroxyethylene (HE) scaffold: exploration of P1' alkoxy residues and an aminoethylene (AE) central core. Bioorg Med Chem. 2010 Feb 15;18(4):1711-23. Epub 2010 Jan 11. PMID:20122837 doi:10.1016/j.bmc.2009.12.051

Page seeded by OCA on Wed Jun 2 08:34:50 2010

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OCA

[1] Bjorklund C, Adolfsson H, Jansson K, Lindberg J, Vrang L, Hallberg A, Rosenquist S, Samuelsson B. Discovery of potent BACE-1 inhibitors containing a new hydroxyethylene (HE) scaffold: exploration of P1' alkoxy residues and an aminoethylene (AE) central core. Bioorg Med Chem. 2010 Feb 15;18(4):1711-23. Epub 2010 Jan 11. PMID:20122837 doi:10.1016/j.bmc.2009.12.051

3i25 | pdb_00003i25

Potent Beta-Secretase 1 hydroxyethylene Inhibitor

About this Structure

Reference

Proteopedia Page Contributors and Editors (what is this?)

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