3l8w | pdb_00003l8w

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File:3l8w.jpg

Template:STRUCTURE 3l8w

Urate oxidase from aspergillus flavus complexed with xanthin

About this Structure

3L8W is a 1 chain structure with sequence from Aspergillus flavus. Full crystallographic information is available from OCA.

Reference

  1. Colloc'h N, el Hajji M, Bachet B, L'Hermite G, Schiltz M, Prange T, Castro B, Mornon JP. Crystal structure of the protein drug urate oxidase-inhibitor complex at 2.05 A resolution. Nat Struct Biol. 1997 Nov;4(11):947-52. PMID:9360612
  2. Gabison L, Chiadmi M, Colloc'h N, Castro B, El Hajji M, Prange T. Recapture of [S]-allantoin, the product of the two-step degradation of uric acid, by urate oxidase. FEBS Lett. 2006 Apr 3;580(8):2087-91. Epub 2006 Mar 10. PMID:16545381 doi:10.1016/j.febslet.2006.03.007
  3. Gabison L, Prange T, Colloc'h N, El Hajji M, Castro B, Chiadmi M. Structural analysis of urate oxidase in complex with its natural substrate inhibited by cyanide: mechanistic implications. BMC Struct Biol. 2008 Jul 20;8:32. PMID:18638417 doi:10.1186/1472-6807-8-32
  4. Colloc'h N, Gabison L, Monard G, Altarsha M, Chiadmi M, Marassio G, Sopkova-de Oliveira Santos J, El Hajji M, Castro B, Abraini JH, Prange T. Oxygen pressurized X-ray crystallography: probing the dioxygen binding site in cofactorless urate oxidase and implications for its catalytic mechanism. Biophys J. 2008 Sep;95(5):2415-22. Epub 2008 Mar 28. PMID:18375516 doi:10.1529/biophysj.107.122184

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