3gic | pdb_00003gic
From Proteopedia
Structure of thrombin mutant delta(146-149e) in the free form
Disease
Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]
About this Structure
3GIC is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Bah A, Carrell CJ, Chen Z, Gandhi PS, Di Cera E. Stabilization of the E* form turns thrombin into an anticoagulant. J Biol Chem. 2009 Jul 24;284(30):20034-40. Epub 2009 May 27. PMID:19473969 doi:10.1074/jbc.M109.012344
Page seeded by OCA on Thu Jun 10 10:53:45 2010
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Thrombin
- Bah, A.
- Carrell, C J.
- Cera, E Di.
- Chen, Z.
- Gandhi, P S.
- Acute phase
- Blood coagulation
- Calcium
- Chymotrypsin fold
- Cleavage on pair of basic residue
- Disease mutation
- Disulfide bond
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydrolase
- Kringle
- Pharmaceutical
- Polymorphism
- Protease
- Secreted
- Serine protease
- Zymogen
