3grw | pdb_00003grw
From Proteopedia
FGFR3 in complex with a Fab
Template:ABSTRACT PUBMED 19381019
Disease
Known disease associated with this structure: Achondroplasia OMIM:[134934], Bladder cancer OMIM:[134934], CATSHL syndrome OMIM:[134934], Cervical cancer, somatic OMIM:[134934], Colorectal cancer, somatic OMIM:[134934], Crouzon syndrome with acanthosis nigricans OMIM:[134934], Hypochondroplasia OMIM:[134934], LADD syndrome OMIM:[134934], Muenke syndrome OMIM:[134934], Nevus, keratinocytic, nonepidermolytic OMIM:[134934], Thanatophoric dysplasia, types I and II OMIM:[134934]
About this Structure
3GRW is a 3 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Qing J, Du X, Chen Y, Chan P, Li H, Wu P, Marsters S, Stawicki S, Tien J, Totpal K, Ross S, Stinson S, Dornan D, French D, Wang QR, Stephan JP, Wu Y, Wiesmann C, Ashkenazi A. Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice. J Clin Invest. 2009 May;119(5):1216-29. doi: 10.1172/JCI38017. Epub 2009, Apr 20. PMID:19381019
Page seeded by OCA on Thu Jun 10 10:55:16 2010
