3hmv | pdb_00003hmv

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Template:STRUCTURE 3hmv

File:3hmv.jpg

Catalytic domain of human phosphodiesterase 4B2B in complex with a tetrahydrobenzothiophene inhibitor

Template:ABSTRACT PUBMED 19525117

About this Structure

3HMV is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Kranz M, Wall M, Evans B, Miah A, Ballantine S, Delves C, Dombroski B, Gross J, Schneck J, Villa JP, Neu M, Somers DO. Identification of PDE4B Over 4D subtype-selective inhibitors revealing an unprecedented binding mode. Bioorg Med Chem. 2009 Jul 15;17(14):5336-41. Epub 2009 Apr 5. PMID:19525117 doi:10.1016/j.bmc.2009.03.061

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