2x99 | pdb_00002x99

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Template:STRUCTURE 2x99

File:2x99.jpg

MAPPING THE CATALYTIC CYCLE OF SCHISTOSOMA MANSONI THIOREDOXIN GLUTATHIONE REDUCTASE BY X-RAY CRYSTALLOGRAPHY

About this Structure

2X99 is a 1 chain structure with sequence from Schistosoma mansoni. Full crystallographic information is available from OCA.

Reference

  1. Angelucci F, Miele AE, Boumis G, Dimastrogiovanni D, Brunori M, Bellelli A. Glutathione reductase and thioredoxin reductase at the crossroad: the structure of Schistosoma mansoni thioredoxin glutathione reductase. Proteins. 2008 Aug 15;72(3):936-45. PMID:18300227 doi:10.1002/prot.21986
  2. Angelucci F, Sayed AA, Williams DL, Boumis G, Brunori M, Dimastrogiovanni D, Miele AE, Pauly F, Bellelli A. Inhibition of Schistosoma mansoni thioredoxin-glutathione reductase by auranofin: structural and kinetic aspects. J Biol Chem. 2009 Oct 16;284(42):28977-85. Epub 2009 Aug 26. PMID:19710012 doi:10.1074/jbc.M109.020701

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