3lxe | pdb_00003lxe

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File:3lxe.jpg

Template:STRUCTURE 3lxe

Human Carbonic Anhydrase I in complex with topiramate

Template:ABSTRACT PUBMED 20505865

About this Structure

3LXE is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Alterio V, Monti SM, Truppo E, Pedone C, Supuran CT, De Simone G. The first example of a significant active site conformational rearrangement in a carbonic anhydrase-inhibitor adduct: the carbonic anhydrase I-topiramate complex. Org Biomol Chem. 2010 Aug 7;8(15):3528-33. Epub 2010 May 27. PMID:20505865 doi:10.1039/b926832d

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