2xjg | pdb_00002xjg
From Proteopedia
STRUCTRE OF HSP90 WITH SMALL MOLECULE INHIBITOR BOUND
About this Structure
2XJG is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Woodhead AJ, Angove H, Carr MG, Chessari G, Congreve M, Coyle JE, Cosme J, Graham B, Day PJ, Downham R, Fazal L, Feltell R, Figueroa E, Frederickson M, Lewis J, McMenamin R, Murray CW, O'Brien MA, Parra L, Patel S, Phillips T, Rees DC, Rich S, Smith DM, Trewartha G, Vinkovic M, Williams B, Woolford AJ. Discovery of (2,4-Dihydroxy-5-isopropylphenyl)-[5-(4-methylpiperazin-1-ylmethyl)-1,3-di hydroisoindol-2-yl]methanone (AT13387), a Novel Inhibitor of the Molecular Chaperone Hsp90 by Fragment Based Drug Design. J Med Chem. 2010 Jul 28. PMID:20662534 doi:10.1021/jm100060b
Page seeded by OCA on Wed Aug 11 23:49:33 2010
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Categories:
- Pages with broken file links
- Homo sapiens
- Callaghan, O.
- Carr, M G.
- Chessari, G.
- Congreve, M.
- Cowan, S.
- Coyle, J E.
- Downham, R.
- Figueroa, E.
- Frederickson, M.
- Graham, B.
- Mcmenamin, R.
- Murray, C W.
- Obrien, M A.
- Patel, S.
- Phillips, T R.
- Williams, G.
- Woodhead, A J.
- Woolford, A J.A.
- Atp binding domain
- Chaperone
- Stress response
