3mxw | pdb_00003mxw

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Template:STRUCTURE 3mxw

File:3mxw.png

Crystal structure Sonic hedgehog bound to the 5E1 fab fragment

Template:ABSTRACT PUBMED 20504762

About this Structure

3MXW is a 3 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Maun HR, Wen X, Lingel A, de Sauvage FJ, Lazarus RA, Scales SJ, Hymowitz SG. Hedgehog pathway antagonist 5E1 binds hedgehog at the pseudo-active site. J Biol Chem. 2010 Aug 20;285(34):26570-80. Epub 2010 May 26. PMID:20504762 doi:10.1074/jbc.M110.112284

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