3msj | pdb_00003msj
From Proteopedia
Structure of bace (beta secretase) in complex with inhibitor
Template:ABSTRACT PUBMED 20656487
About this Structure
3MSJ is a 3 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Madden J, Dod JR, Godemann R, Kraemer J, Smith M, Biniszkiewicz M, Hallett DJ, Barker J, Dyekjaer JD, Hesterkamp T. Fragment-based discovery and optimization of BACE1 inhibitors. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5329-33. Epub 2010 Jun 27. PMID:20656487 doi:10.1016/j.bmcl.2010.06.089
Page seeded by OCA on Wed Sep 1 09:21:31 2010
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Memapsin 2
- Barker, J.
- Godemann, R.
- Kramer, J.
- Madden, J.
- Smith, M A.
- Alzheimer's disease
- Amyloid precursor protein secretase
- Aspartic endopeptidase
- Aspartic protease
- Aspartyl protease
- Base
- Beta-secretase
- Fluorescence polarisation
- Fragment-based drug design
- Glycoprotein
- Hydrolase
- Protease
- Transmembrane
- Zymogen
